40 mg famotidine pill identifier
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The active ingredient in famotidine tablets USP is a histamine H 2 -receptor antagonist. Famotidine, USP is [1-Amino[[[2-[ diaminomethylene amino]thiazolyl]methyl]thio] propylidene] sulfamide and has the following structural formula:. Famotidine, USP is a white to pale yellow crystalline compound that is freely soluble in glacial acetic acid, slightly soluble in methanol, very slightly soluble in water, and practically insoluble in ethanol. Each tablet for oral administration contains either 20 mg or 40 mg of famotidine, USP and has the following inactive ingredients: colloidal silicon dioxide, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, pregelatinized corn starch, sodium starch glycolate, talc, titanium dioxide, yellow iron oxide. Famotidine is a competitive inhibitor of histamine H 2 -receptors. The primary clinically important pharmacologic activity of famotidine is inhibition of gastric secretion. Both the acid concentration and volume of gastric secretion are suppressed by famotidine, while changes in pepsin secretion are proportional to volume output.
40 mg famotidine pill identifier
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Product Characteristics. In trials of patients with pathological hypersecretory conditions such as Zollinger-Ellison syndrome with or without multiple endocrine neoplasias, famotidine significantly inhibited gastric acid secretion and controlled associated symptoms. Convulsions, in patients with impaired renal function, have been reported very rarely.
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Famotidine tablets is a histamine-2 H 2 receptor antagonist indicated 1 :. Adult and Pediatric Patients. Administration 2. History of serious hypersensitivity reactions e. The most common adverse reactions are: headache, dizziness, constipation, and diarrhea. Famotidine tablets are indicated in adult and pediatric patients 40 kg and greater for the treatment of:. Table 1 shows the recommended dosage of famotidine 20 mg and 40 mg tablets in adult and pediatric patients weighing 40 kg and greater with normal renal function.
40 mg famotidine pill identifier
Famotidine is used to treat stomach ulcers gastric and duodenal , erosive esophagitis heartburn or acid indigestion , and gastroesophageal reflux disease GERD. GERD is a condition where the acid in the stomach washes back up into the esophagus. It is also used to treat certain conditions where there is too much acid in the stomach eg, Zollinger-Ellison syndrome, multiple endocrine neoplasia. Famotidine belongs to the group of medicines known as histamine H2-receptor antagonists or H2-blockers. It works by decreasing the amount of acid produced by the stomach. This medicine is available with your doctor's prescription and also without a prescription.
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Some dosage adjustments may require switching to other formulations of famotidine e. DailyMed will deliver notification of updates and additions to Drug Label information currently shown on this site through its RSS feed. The nocturnal intragastric pH was raised by evening doses of 20 and 40 mg of famotidine to mean values of 5 and 6. Gastrointestinal: elevated liver enzymes, vomiting, nausea, abdominal discomfort, anorexia, dry mouth. Version Files Aug 22, 9 current download Oct 5, 8 download Jul 14, 7 download Sep 16, 6 download Jun 12, 5 download Dec 24, 4 download Aug 6, 3 download Oct 24, 2 download Dec 28, 1 download. Famotidine is incompletely absorbed. In pediatric patients 11 to 15 years of age, oral doses of 0. Pharmacodynamics of famotidine were evaluated in 5 pediatric patients 2 to 13 years of age using the sigmoid E max model. In contrast, pediatric patients 0 to 3 months of age had famotidine clearance values that were 2 to 4 fold less than those in older pediatric patients and adults. Enrolled patients were diagnosed primarily by history of vomiting spitting up and irritability fussiness. Reduction of the risk of DU recurrence d. In postmarketing experience, CNS adverse reactions have been reported in elderly patients with and without renal impairment receiving famotidine [see Warnings and Precautions 5. Most adult patients heal within 4 weeks; there is rarely reason to use famotidine at full dosage for longer than 6 to 8 weeks. Famotidine, USP is a white to pale yellow crystalline compound that is freely soluble in glacial acetic acid, slightly soluble in methanol, very slightly soluble in water, and practically insoluble in ethanol.
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Gastrointestinal: elevated liver enzymes, vomiting, nausea, abdominal discomfort, anorexia, dry mouth. Most adult patients heal within 4 weeks; there is rarely reason to use famotidine at full dosage for longer than 6 to 8 weeks. Controlled trials have not extended beyond one year. In a study examining the effect of famotidine on gastric pH and duration of acid suppression in pediatric patients, four pediatric patients ages 11 to 15 years of age using the oral formulation at a dose of 0. Bioavailability studies of 8 pediatric patients 11 to 15 years of age showed a mean oral bioavailability of 0. Studies with famotidine in man, in animal models, and in vitro have shown no significant interference with the disposition of compounds metabolized by the hepatic microsomal enzymes, e. These data suggest that the relationship between serum concentration of famotidine and gastric acid suppression is similar to that observed in one study of adults Table 7. Famotidine, USP is [1-Amino[[[2-[ diaminomethylene amino]thiazolyl]methyl]thio] propylidene] sulfamide and has the following structural formula:. However, no clinically significant interaction with metformin, a substrate for MATE-1, was observed. Short-term treatment of active duodenal ulcer Most adult patients heal within 4 weeks; there is rarely reason to use famotidine at full dosage for longer than 6 to 8 weeks.
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