Adriamycin

Federal government websites often end in. The site adriamycin secure. Adriamycin doxorubicin hydrochloride is an antineoplastic agent effective against a wide range of malignant conditions, although adriamycin toxicity, especially dose-dependent cardiomyopathy, adriamycin, limits its long-term use. Previous mediastinal radiation therapy or left ventricular dysfunction and advanced age increase the risk of this complication developing.

Doxorubicin , sold under the brand name Adriamycin among others, is a chemotherapy medication used to treat cancer. Common side effects include hair loss , bone marrow suppression , vomiting , rash, and inflammation of the mouth. Doxorubicin was approved for medical use in the United States in It is indicated to treat multiple myeloma in combination with bortezomib. Doxorubicin is commonly used to treat some leukemias and lymphomas , as well as cancers of the bladder , breast , stomach , lung , ovaries , thyroid , soft tissue sarcoma , multiple myeloma , and others. Doxil see below is used primarily for the treatment of ovarian cancer where the disease has progressed or recurred after platinum-based chemotherapy , or for the treatment of AIDS -related Kaposi's sarcoma.

Adriamycin

For the best browsing experience please enable JavaScript. Instructions for Microsoft Edge and Internet Explorer , other browsers. It is a treatment for a number of different cancer types. You might have doxorubicin in combination with other cancer drugs. Doxorubicin is a type of chemotherapy drug called an anthracycline. It slows or stops the growth of cancer cells by blocking an enzyme called topo isomerase 2. Cancer cells need this enzyme to divide and grow. You might have treatment through a long plastic tube that goes into a large vein in your chest. The tube stays in place throughout the course of treatment. This can be a:. You might have treatment through a thin short tube a cannula that goes into a vein in your arm. You have a new cannula each time you have treatment. Sometimes, doxorubicin may be given directly into the bladder to treat cancer of the bladder lining. This is called intravesical chemotherapy and the side effects are different to doxorubicin given into a vein. You usually have this type of chemotherapy as a course of several cycles of treatment.

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Doxorubicin injection is used together with other medicines to treat cancer of the blood, lymph system, bladder, breast, stomach, lungs, ovaries, thyroid, nerves, kidneys, bones, and soft tissues, including muscles and tendons. It may also be used to treat other kinds of cancer, as determined by your doctor. Doxorubicin belongs to the group of medicines known as antineoplastics. It seems to interfere with the growth of cancer cells, which are then eventually destroyed by the body. Since the growth of normal body cells may also be affected by doxorubicin, other effects will also occur.

Doxorubicin , sold under the brand name Adriamycin among others, is a chemotherapy medication used to treat cancer. Common side effects include hair loss , bone marrow suppression , vomiting , rash, and inflammation of the mouth. Doxorubicin was approved for medical use in the United States in It is indicated to treat multiple myeloma in combination with bortezomib. Doxorubicin is commonly used to treat some leukemias and lymphomas , as well as cancers of the bladder , breast , stomach , lung , ovaries , thyroid , soft tissue sarcoma , multiple myeloma , and others. Doxil see below is used primarily for the treatment of ovarian cancer where the disease has progressed or recurred after platinum-based chemotherapy , or for the treatment of AIDS -related Kaposi's sarcoma. The most dangerous side effect of doxorubicin is dilated cardiomyopathy , leading to congestive heart failure. Doxorubicin-induced cardiomyopathy typically results in dilated cardiomyopathy, with all four cardiac chambers being enlarged. Another common and potentially fatal complication of doxorubicin is typhlitis , an acute life-threatening inflammation of the bowel. Chemotherapy can cause reactivation of hepatitis B , and doxorubicin-containing regimens are no exception.

Adriamycin

Doxorubicin is used to treat different types of cancers that affect the breast, bladder, kidneys, ovaries, thyroid, stomach, lungs, bones, nerve tissues, joints, and soft tissues. Doxorubicin is also used to treat Hodgkin lymphoma, non-Hodgkin lymphoma, and certain types of leukemia. Doxorubicin may also be used for purposes not listed in this medication guide. You should not use this medicine if you are allergic to doxorubicin or similar medications doxorubicin, daunorubicin, epirubicin, idarubicin, mitoxantrone , or if you have:. Tell your doctor about all other cancer medicines or radiation treatments you have received in the past. Using doxorubicin may increase your risk of developing a bone marrow disease or other types of leukemia later in life. Ask your doctor about your specific risk. You may need to have a negative pregnancy test before starting this treatment.

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There is some evidence for antimalarial activity for doxorubicin and similar compounds. Talk to your team about this. September A strain of Streptomyces was mutated using N -nitroso- N -methyl urethane, and this new strain produced a different, red-colored antibiotic. Or you may have lots of tiny red spots or bruises on your arms or legs known as petechiae. Unlike Doxil, the Myocet liposome does not have a polyethylene glycol coating, and therefore does not result in the same rate of PPE. Find out more about your cancer type. Although not all of these side effects may occur, if they do occur they may need medical attention. Retrieved 12 July In , a compound similar in structure to doxorubicin was found to inhibit plasmepsin II, an enzyme unique to the malarial parasite Plasmodium falciparum. British Medical Association. Previous mediastinal radiation therapy or left ventricular dysfunction and advanced age increase the risk of this complication developing.

Doxorubicin injection is used together with other medicines to treat cancer of the blood, lymph system, bladder, breast, stomach, lungs, ovaries, thyroid, nerves, kidneys, bones, and soft tissues, including muscles and tendons. It may also be used to treat other kinds of cancer, as determined by your doctor. Doxorubicin belongs to the group of medicines known as antineoplastics.

Talk with your doctor before you use this medicine if you plan to have children. This liposome-encapsulated form is also approved by the FDA for treatment of ovarian cancer and multiple myeloma. Archived from the original on 1 August Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. Bibcode : NatCo Cancer Treat Rep. A nurse or other trained health professional will give you this medicine in a hospital or cancer treatment center. Talk to your doctor or nurse about effective contraception before starting treatment. May Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:.