Apireks surup

Last updated on For the relief of mild to moderate pain including rheumatic and muscular pain, backache, neuralgia, migraine, headache, dental pain, dysmenorrhoea, feverishness and for the relief of the symptoms of apireks surup and influenza. For the relief of migraine-headaches, backache, dental pain, neuralgia and period pains as well as rheumatic and muscular pains, apireks surup.

Apireks Suspension Generic Name s : Ibuprofen. Why it's used Apireks Suspension is used to relieve mild to moderate pain from a headache , menstrual periods, muscle ache, common cold , toothache, or a backache. This medicine works by reducing the activity of a chemical in the body that causes pain and swelling. Apireks is also used to reduce fever. It is also used to relieve pain associated with the inflammation, swelling and stiffness of the joints caused by rheumatoid arthritis and osteoarthritis. When not to use Apireks Suspension cannot be used to treat pain before and after the time of a heart operation.

Apireks surup

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Most postmarketing reports of fatal GI events occurred in elderly or debilitated patients. Typical Dosage The typical dose of Apireks for adults is mg every 4 to 6 hours apireks surup more than mg in one day.

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Apireks is a non-selective inhibitor of cyclooxygenase, an enzyme invovled in prostaglandin synthesis via the arachidonic acid pathway. Its pharmacological effects are believed to be due to inhibition cylooxygenase-2 COX-2 which decreases the synthesis of prostaglandins involved in mediating inflammation, pain, fever and swelling. Antipyretic effects may be due to action on the hypothalamus, resulting in an increased peripheral blood flow, vasodilation, and subsequent heat dissipation. Inhibition of COX-1 is thought to cause some of the side effects of ibuprofen including GI ulceration. Apireks is administered as a racemic mixture. The R-enantiomer undergoes extensive interconversion to the S-enantiomer in vivo. The S-enantiomer is believed to be the more pharmacologically active enantiomer.

Apireks surup

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Elimination half-life is approximately 2 hours. Gastro-intestinal GI bleeding, ulceration, or perforation, which can be fatal, has been reported with all NSAIDs at any time during treatment, with or without warning symptoms or a previous history of serious GI effects including ulcerative colitis, Crohn's disease. However, please discuss with your doctor or pharmacist, if you feel unwell or sick. Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors and the elderly. The information provided in Incompatibilities of Apireks is based on data of another medicine with exactly the same composition as the Apireks. The physician must be continually on the alert and should use the drug with extra care in the presence of controlled infection and in infants at risk of infection. Inform pregnant women to avoid use of Apireks and other NSAIDs starting at 30 weeks gestation because of the risk of the premature closing of the fetal ductus arteriosus. If a patient treated with Apireks has any signs or symptoms of anemia, monitor hemoglobin or hematocrit. As a non-steroidal anti-inflammatory drug NSAID , ibuprofen may mask the usual signs and symptoms of infection. Sulfonylureas Apireks Suspension interacts with sulfonylureas, which are medicines used to treat high blood sugar type 2 diabetes. The combined usage of these medicines will lead to an increased risk of gastrointestinal bleeding. Caution is required if Brufen is administered to patients suffering from, or with a previous history of, bronchial asthma, chronic rhinitis or allergic diseases since NSAIDs have been reported to precipitate bronchospasm, urticaria or angioedema in such patients. To be taken preferably with or after food.

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Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. No clinically relevant effect is considered to be likely for occasional ibuprofen use. ATC code: M01AE01 Ibuprofen is a propionic acid derivative with analgesic, anti-inflammatory and antipyretic activity. Apireks Side-effects The following side-effects may commonly occur when using Apireks Suspension. Within each frequency grouping, adverse reactions are presented in order of decreasing seriousness. Non Steroidal Anti-Inflammatory Drugs There may be an interaction of Apireks with aspirin , which is used to reduce fever and relieve mild to moderate pain. However, if the time for the next dose is almost there, then the missed dose should be skipped, and the regular dosing schedule should be continued. Caution is required in patients with certain conditions: - Systemic lupus erythematosus as well as those with mixed connective tissue disease due to increased risk of aseptic meningitis. Immune system disorders Uncommon: Hypersensitivity reactions with urticaria and pruritus. Patients appear to be at highest risk for these reactions early in the course of therapy: the onset of the reaction occurring in the majority of cases within the first month of treatment. Ulcerative stomatitis, gastritis. Published animal studies have shown that administration of prostaglandin synthesis inhibitors has the potential to disrupt prostaglandin- mediated follicular rupture required for ovulation. In case of overdose, get medical help or contact a Poison Control Center right away. Experimental data suggest that Apireks may competitively inhibit the effect of low dose aspirin acetylsalicylic acid on platelet aggregation when they are dosed concomitantly.