Curcuma pubmed

Natural polyphenols provide established efficacy against chemically induced tumor growth with fewer side effects. They can sensitize cells to curcuma pubmed therapies and increase the effectiveness of biotherapy.

Akceptuję ogólne warunki użytkowania i politykę prywatności. Oznacza to, że dokładnie wiesz ile pożądanej substancji spożywasz, w przeciwieństwie do ekstraktów bez standaryzacji, w których ilość kurkuminy czy piperyny może być bardzo małą. Nie zawiera tzw. Świetna opcja mogąca zainteresować osoby borykające się ze stanami zapalnymi, lub chcące zadziałać prozdrowotnie na swój organizm, nie tylko dla sportowców. Według wielu badan naukowych, ekstrakt z kurkumy może przejawiać następujące właściwości i działania:.

Curcuma pubmed

Federal government websites often end in. The site is secure. The tumor-bearing rats underwent food restriction combined with laxative FRL treatment in order to model the nutritional and digestive symptoms of patients with hepatocellular carcinoma. The FRL rat model was established by alternate-day food restriction and the oral administration of Glauber's salt sodium sulfate , based on which the OHC model was then established. Differences in the TCRVβCDR3 repertoire in the rat thymus, liver and hepatocellular carcinoma tissues were analyzed by polymerase chain reaction. However, no anti-hepatoma effects were evident in the rats treated with TP5. The Chinese herbal formulation Jianpijiedu JPJD , also known as Fuzheng Jiedu, has been proposed as a complementary therapy for the treatment of hepatocellular carcinoma due to its ability to enhance the absorption and transportation of nutrients and to reduce tumor burden. A randomized clinical trial of patients with hepatocellular carcinoma has shown that this formulation can effectively promote quality of life and liver function if combined with intra-arterial chemotherapy 1. Furthermore, studies have indicated that JPJD can improve survival time, reduce pulmonary metastasis 2 and maintain the body and visceral weight of nude mice transplanted with human hepatocellular carcinoma tissue 3. These previous findings indicate that JPJD may be able to improve digestive and absorptive functions and the quality of life in patients with hepatocellular carcinoma.

Yang, Y. Bioengineered 12, — Lee, Y.

Curcumin, the active ingredient in turmeric, is gaining increasing attention due to its potential health benefits, especially in the context of its immunomodulatory and anticancer properties. The aim of this review was to discuss recent findings regarding the impact of curcumin on the immune system and its potential applications in anticancer therapy. The paper was created based on the Pubmed and Scholar database. Studies have confirmed that curcumin, especially in the form of nanocurcumin, exhibits significant immunomodulatory effects. It reduces the number of Th17 cells, increases Treg cells, and regulates the expression of pro-inflammatory cytokines, which is crucial in controlling autoimmune reactions. Furthermore, it demonstrates anticancer activity by inhibiting the growth of cancer cells, stimulating apoptosis, and enhancing the effectiveness of anticancer therapy.

Turmeric Curcuma longa and its constituent, curcumin, have been used for their therapeutic properties for a long time. Most of the medicinal impacts of turmeric and curcumin might be attributed to their anti-inflammatory, antinociceptive, and antioxidant effects. In the present review, the preventive and therapeutic potentials of turmeric and its active constituent, curcumin, on inflammatory disorders and pain as well as patents related to their analgesic and anti-inflammatory effects, have been summarized to highlight their value on human health. Several documents and patents disclosed the significance of turmeric and curcumin to apply in several therapeutic, medicinal, and pharmaceutical fields. These phytocompounds could be applied as a supplementary therapy in phytotherapy, inflammatory disorders such as arthritis, inflammatory bowel diseases, osteoarthritis, psoriasis, dermatitis, and different types of pain including neuropathic pain. However, because of inadequate clinical trials, further high-quality studies are needed to firmly establish the clinical efficacy of the plant. Consistent with the human tendency to the usage of phytocompounds rather than synthetic drugs, particular consideration must be dedicated to bond the worth of turmeric and curcumin from basic sciences to clinical applications. Keywords: Curcuma longa; anti-inflammatory; antinociceptive; curcumin; pain; turmeric. Abstract Turmeric Curcuma longa and its constituent, curcumin, have been used for their therapeutic properties for a long time. Publication types Review.

Curcuma pubmed

Curcuma longa turmeric has a long history of use in Ayurvedic medicine as a treatment for inflammatory conditions. Turmeric constituents include the three curcuminoids: curcumin diferuloylmethane; the primary constituent and the one responsible for its vibrant yellow color , demethoxycurcumin, and bisdemethoxycurcumin, as well as volatile oils tumerone, atlantone, and zingiberone , sugars, proteins, and resins. While numerous pharmacological activities, including antioxidant and antimicrobial properties, have been attributed to curcumin, this article focuses on curcumin's anti-inflammatory properties and its use for inflammatory conditions. Curcumin's effect on cancer from an anti-inflammatory perspective will also be discussed; however, an exhaustive review of its many anticancer mechanisms is outside the scope of this article. Research has shown curcumin to be a highly pleiotropic molecule capable of interacting with numerous molecular targets involved in inflammation. Based on early cell culture and animal research, clinical trials indicate curcumin may have potential as a therapeutic agent in diseases such as inflammatory bowel disease, pancreatitis, arthritis, and chronic anterior uveitis, as well as certain types of cancer. Because of curcumin's rapid plasma clearance and conjugation, its therapeutic usefulness has been somewhat limited, leading researchers to investigate the benefits of complexing curcumin with other substances to increase systemic bioavailability. Numerous in-progress clinical trials should provide an even deeper understanding of the mechanisms and therapeutic potential of curcumin.

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Tumur, Z. Prostate tumor inhibition by quercetin in vivo in a mouse model is upregulated by the expression of Thrombospondin-1, which inhibits tumor propagation Yang F. Luteolin inhibits the progression of cancerous cells, protects from carcinogenic stimuli, activates cell division blocks, and helps in the initiation of cell death via activating numerous signaling pathways. Tseng, T. Downloads PDF. A Glauber's salt solution was prepared, as described above. FRL-OHC model establishment was observed to significantly inhibit the body weight gain of the rats, leading to a compensatory increase of the viscera and the proliferation of hepatocellular carcinoma. Silibinin enhances ultraviolet B-induced apoptosis in MCF-7 human breast cancer cells. Asian pac. The use, distribution or reproduction in other forums is permitted, provided the original author s and the copyright owner s are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. World J Gastroenterol. Steroid Biochem. The role of polyphenols in human health and food systems: A mini-review. Apigenin-induced apoptosis is enhanced by inhibition of autophagy formation in HCT human colon cancer cells.

It aids in the management of oxidative and inflammatory conditions, metabolic syndrome, arthritis, anxiety, and hyperlipidemia. It may also help in the management of exercise-induced inflammation and muscle soreness, thus enhancing recovery and performance in active people.

Cancer Cell Int. Hepatobiliary Pancreat Dis Int. Tobacco smoking and liver cancer risk: Potential avenues for carcinogenesis. Cinnamomum species: Bridging phytochemistry knowledge, pharmacological properties and toxicological safety for health benefits. Quercetin modulates signaling pathways and induces apoptosis in cervical cancer cells. Remember me. Human cancer databases review. The effects of nanocurcumin on Treg cell responses and treatment of ankylosing spondylitis patients: A randomized, double-blind, placebo-controlled clinical trial. Quercetin inhibits angiogenesis through thrombospondin-1 upregulation to antagonize human prostate cancer PC-3 cell growth in vitro and in vivo. Table III. Rats were housed individually at 23±1°C with a 12—12 h light-dark cycle and a feeding regimen of tap water ad libitum and alternate-day food restriction In human hepatocellular carcinoma HCC , silibinin powerfully repressed the growth of HepG2 and Hep3B cell lines and showed relatively more potent cytotoxicity in Hep3B cells, causing apoptosis induction.