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Federal government websites often end in. The site is secure. The data presented in this study are available on request from the corresponding author. The data are not publicly available due to personal data protection regulations. This prospective cohort study included health care workers who had received two prime shots with CoronaVac. The mean age of health care workers who participated in the project was At the end of the 6th month, no antibodies were detected in The antibody concentrations of the 6th month were found to have increased by an average of 5. The vaccine research rally reached more than 50 vaccine candidates against COVID at the end of There were included different platforms, such as nucleic acid, live attenuated virus, protein subunit, and viral vector vaccines [ 4 ]. In a short time, several large clinical trials have demonstrated the clinical efficacy and safety of certain COVID vaccines.
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One of the important results of the study is that a booster dose is needed at the end of the sixth month. Stay informed of issues for this journal through your RSS reader. Author Contributions Conceptualization, H. PDF English. Although ICIQ-SF decrease after treatment, the difference was not statistically significant although there was a trend toward significance, which may become significant with larger group sizes Table 3. Shang W. This was a prospective cohort study and constituted the third step of a vaccine efficacy and safety project. To avoid this, it is accepted that third shots would be shifted to mRNA- or protein-based vaccines following the prime series with vector vaccines. In a short time, several large clinical trials have demonstrated the clinical efficacy and safety of certain COVID vaccines. The mean age of health care workers who participated in the third step of our study was Data Availability Statement The data presented in this study are available on request from the corresponding author. We aimed in this study to evaluate whether the mixed application of the inactivated vaccine and the mRNA vaccine BNTb2 had a superiority in antibody response and safety compared to homologous vaccine application. A total of patients with the mean age of
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Last updated on February 17, The vaccines were transferred, stored, and administered following cold-chain principles already in use by, and therefore familiar to, health institutions performing vaccinations. The closest one is a 2 min walk away. A four-fold increase in cellular immune response was also observed. This prospective cohort study included health care workers who had received two prime shots with CoronaVac. Food and Drug Administration U. The initial report showed that there was an increase in systemic reactogenicity after the boost dose, as reported by participants in heterologous vaccine schedules in comparison to homologous vaccine schedules [ 17 ]. It should be noted that the fact that there is a higher proportion of anti-S-RBD response in those re-immunised with BNT does not imply that these individuals are more protected, since this study does not assess protection, but levels of antibodies against the antigen. It stops nearby at PM. As an example, nucleic acid-based vaccines such as DNA vaccines or mRNA vaccines are easy to design, but they may not be immunogenic. The vaccine research rally reached more than 50 vaccine candidates against COVID at the end of
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