Milk thistle zararları

Federal government websites often end in. The site is secure. Widespread use of herbal drugs because of their protective effects on different organs toxicity has been shown in many studies.

How to use: For adults, it is recommended to take 1 capsule 2 times a day after meals and dissolve 1 sachet in a glass ml of water once a day and take after meals. Recommended consumption date and lot number are on the packaging. Store at room temperature, protect from heat and light. Additional Information: Do not exceed the recommended daily dose. Supplements cannot replace a normal diet.

Milk thistle zararları

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Nutr Metab. Planta Med.

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One of the active ingredients in milk thistle called silymarin is extracted from the plant's seeds. Silymarin is believed to have antioxidant properties. Milk thistle is sold as an oral capsule, tablet and liquid extract. People mainly use the supplement to treat liver conditions. If you have diabetes, use milk thistle with caution, since the supplement might lower blood sugar. There is also concern that milk thistle might affect estrogen levels.

Milk thistle zararları

Milk thistle is a natural herb with antioxidant and anti-inflammatory properties. Also known by its scientific name, Silybum marianum, milk thistle grows mostly in California, although it can be grown in many other warm climates as well. Other benefits include promoting healthy digestive function, increasing bile production , decreasing inflammation and soothing the mucous membranes throughout the body. The milk thistle plant is a popular herb that has actually been used for over 2, years. The plant is native to the Mediterranean region and a member of the Asteraceae plant family, which also includes other plants like sunflowers and daisies. Milk thistle is commonly used for everything from weight loss to skin health to promoting breast milk production. However, while there are many different potential benefits, it is most well-known for being a natural liver supporter and is sometimes used to help treat liver diseases such as cirrhosis, jaundice and hepatitis, as well as gallbladder problems. There are a variety of milk thistle products available, and the seeds and leaves of the milk thistle plant can be consumed either in pill, powder, tincture, extract or tea form. The seeds can actually be eaten completely raw, too, but usually people prefer to take a milk thistle extract or supplement in order to consume a higher dose and see greater results. As a liver support and liver aid, milk thistle acts as a powerful liver cleanser by rebuilding liver cells, reducing liver damage and removing toxins from the body that are processed through the liver.

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Consult your doctor in case of pregnancy and lactation, illness or drug use. In another study, cisplatin and ifosfamide-induced renal toxicity can be antagonized by silymarin without reducing anti-tumor efficacy of these drugs 6 , 44 - Clinical Epidemiology 6 Results showed that ethanolic extract had no effect on the duration of mice immobility while the aqueous extract significantly diminished it, concluding that aqueous extract of silymarin has antidepressant effect in animal models A flavonoid antioxidant, silymarin, affords exceptionally high protection against tumor promotion in the SENCAR mouse skin tumorigenesis model. Pizzo,et al. Involvement of multiple molecular events in pyrogallol-induced hepatotoxicity and silymarin-mediated protection: Evidence from gene expression profiles. Food Supplement Approval Number: Basic Clin Pharmacol Toxicol. Evid Based Complement Alternat Med. Silybinin efficacy against human hepatocellular. J Alternat Complement Med.

Milk thistle Silybum marianum is a herb loaded with antioxidants and is known for its anti-inflammatory properties. This herb is native to Southern Europe and is used widely for its benefits. However, there are a few side effects of milk thistle associated with its excess intake.

As the results have been conflicting, clinical efficacy of silymarin in chronic liver diseases has not yet been demonstrated 25 - Mol Carcinog. Effect of silymarin on biochemical parameters of oxidative stress in aged and young rat brain. Oncol Rep. Epub Jun Pre-treatment of male mice with silymarin modulated the alteration of oxidative stress, cell cycle, cytoskeletal network, cell—cell adhesion, extra-cellular matrix, inflammation, apoptosis, cell-signaling and intermediary metabolism that was induced by pyrogallol. In vitro experiments have been verified that two components of silymarin, silybin A and B are able to inhibit T-cell proliferation and proinflammatory cytokine secretion in a dose-dependent manner. Silymarin was administrated 20 days after 9 weeks treatment with alloxan and it was effective on the renal tissue injuries. However, numerous in vitro and in vivo experiments containing cancer models did not show significant dissimilarity in biological activity between silymarin and silybin According to previous studies, silymarin has antioxidant activities in the central nervous system, which enables it to enter the CNS via the blood—brain barrier BBB 48 -