Salvia miltiorrhiza

Chinese Medicine volume 5Article number: 22 Cite this article. Metrics details.

Federal government websites often end in. The site is secure. Salvia miltiorrhiza Bunge, also known as Danshen in Chinese, has been widely used to treat cardiovascular diseases CVD in China and other Asia countries. Here, we summarize literatures of the historical traditional Chinese medicine TCM interpretation of the action of Salvia miltiorrhiza, its use in current clinical trials, its main phytochemical constituents and its pharmacological findings by consulting Pubmed, China Knowledge Resource Integrated, China Science and Technology Journal, and the Web of Science Databases. Since , 39 clinical trials have been identified that used S.

Salvia miltiorrhiza

Salvia miltiorrhiza Bunge SM is a very popular medicinal plant that has been extensively applied for many years to treat various diseases, especially coronary heart diseases and cerebrovascular diseases, either alone or in combination with other Chinese plant-based medicines. Although a large number of studies on SM have been performed, they are scattered across a variety of publications. The present review is an up-to-date summary of the published scientific information about the traditional uses, chemical constituents, pharmacological effects, side effects, and drug interactions with SM, in order to lay the foundation for further investigations and better utilization of SM. SM contains diverse chemical components including diterpenoid quinones, hydrophilic phenolic acids, and essential oils. Many pharmacological studies have been done on SM during the last 30 years, focusing on the cardiovascular and cerebrovascular effects, and the antioxidative, neuroprotective, antifibrotic, anti-inflammatory, and antineoplastic activities. The research results strongly support the notion that SM has beneficial therapeutic properties and has a potential of being an effective adaptogenic remedy. Published by Elsevier B. All rights reserved. Abstract Salvia miltiorrhiza Bunge SM is a very popular medicinal plant that has been extensively applied for many years to treat various diseases, especially coronary heart diseases and cerebrovascular diseases, either alone or in combination with other Chinese plant-based medicines. Publication types Research Support, Non-U. Gov't Review.

Involvements of calcium channel and potassium channel in Danshen and Gegen decoction induced vasodilation in porcine coronary LAD artery.

The specific epithet miltiorrhiza means "red ochre root". Chemical compounds isolated from Salvia miltiorrhiza include salvianolic acid or salvianolic acid B , [3] [4] dihydrotanshinone , miltirone , [5] tanshinone I , and tanshinone IIA. The 30 cm 0. Flowers grow in whorls, with light purple to lavender blue corollas that are approximately 2. Salvia miltiorrhiza prefers well-drained soil, with about half a day of sunlight. Danshen may potentiate the effects of the anticoagulation drug warfarin , possibly causing bleeding complications.

The specific epithet miltiorrhiza means "red ochre root". Chemical compounds isolated from Salvia miltiorrhiza include salvianolic acid or salvianolic acid B , [3] [4] dihydrotanshinone , miltirone , [5] tanshinone I , and tanshinone IIA. The 30 cm 0. Flowers grow in whorls, with light purple to lavender blue corollas that are approximately 2. Salvia miltiorrhiza prefers well-drained soil, with about half a day of sunlight. Danshen may potentiate the effects of the anticoagulation drug warfarin , possibly causing bleeding complications.

Salvia miltiorrhiza

Thank you for visiting nature. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser or turn off compatibility mode in Internet Explorer.

Antiques yeah

Therefore, multi-targeted therapeutic interventions would likely be required for effective management of CVD. Symptoms of angina pectoris: Markedly improved However, the potential pharmacological effects are still required to be studied by more strong scientific evidences. Co-administration of Danshen and warfarin should be avoided or closely monitored [ 54 ]. FEBS J. Voulgari C. Neuroprotection is also a potential treatment [ 5 ]. Panax notoginseng Sanqi is also used to treat vascular disorders. Qiu P. J Clin Pharmacol. Significant effect: Clinical symptoms of heart failure and physical signs disappeared; Cardiac function improved by 2 levels.

Federal government websites often end in. The site is secure.

Rapid Commun. Correspondence to Ching-Liang Hsieh. Institute for Traditional Medicine. Download references. As leukocytes are mediated via the combination of surface receptors of CD18 and CD11b and intracellular adhesion molecules of endothelium, the neuroprotection capability of Danshen may be associated with the inhibition of leukocyte adherence to the endothelium [ 40 ]. Ding M. J Cell Biochem. Conclusion and outlook S. As apoptosis is a major pathway leading to neuronal death, Tan IIB is neuroprotective [ 47 ]. Tanshinone II A; 6. Sheng Y. Clinical observation of patients with heart medicine by salvia miltiorrhiza preparation and combine traditional Chinese and western medicine nursing. Currently, more than compounds have been identified from S. Life Sci.