Sitagliptin maximum dose per day

Take this medicine exactly as directed by your doctor.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects. This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

Sitagliptin maximum dose per day

Januvia sitagliptin is a prescription brand-name medication. The Food and Drug Administration FDA has approved it to treat type 2 diabetes in adults, in combination with exercise and a balanced diet. Januvia is available as a generic medication called sitagliptin. Sitagliptin is the active drug in Januvia. For information about the dosage of Januvia, including its form, strengths, and how to take the drug, keep reading. For a comprehensive look at Januvia, see this article. When taking Januvia, always follow the dosage prescribed by your doctor. The following information describes Januvia doses that are commonly used or recommended. But be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs. The recommended dosage of Januvia for treating type 2 diabetes is mg once daily. Note: People with kidney problems may need a lower dosage of Januvia than usual. Januvia is meant to be used as a long-term treatment. This may be taken as mg or mg tablets, or a mg tablet.

Financial Services. The dosages in this article are typical dosages provided by the drug manufacturer. Plasma DPP-4 activity was assessed at trough, 24 h following dosing on day 7; percent DPP-4 inhibition was corrected for sample assay dilution.

Objective: In clinical trials, the degree of glucose lowering with sitagliptin has been correlated with the magnitude of dipeptidyl peptidase-4 DPP-4 inhibition over 24 h. However, sitagliptin mg once daily provided numerically greater percent plasma DPP-4 inhibition compared with mg once daily. The purpose of this study was to evaluate whether sitagliptin mg once daily provides greater improvement in glycemic efficacy as assessed by weighted mean glucose WMG over 24 h relative to sitagliptin mg once daily and to relate the percent DPP-4 inhibition achieved with these doses to any between-treatment differences in glycemic efficacy. Each of the treatment periods was 7 days in duration, with day washout periods between treatments. After each treatment period, patients underwent blood sampling at various time points over 24 h to determine h WMG. Plasma DPP-4 activity was assessed at trough, 24 h following dosing on day 7; percent DPP-4 inhibition was corrected for sample assay dilution. Following a planned interim analysis, the study was stopped because the h WMG values were not different between the sitagliptin doses.

Back to Sitagliptin. Your doctor might prescribe a lower dose of 25mg or 50mg a day if you have problems with your kidneys. Take sitagliptin once a day. You can take it at any time, for example, in the morning or in the evening. But try to take it at the same time every day. Take your tablet with a drink of water. Swallow the tablet whole, without breaking it.

Sitagliptin maximum dose per day

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects. This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

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Follow your doctor's orders or the directions on the label. Missed dose. But be sure to take the dosage your doctor prescribes for you. When taking Januvia, always follow the dosage prescribed by your doctor. Plasma DPP-4 activity was assessed at trough, 24 h following dosing on day 7; percent DPP-4 inhibition was corrected for sample assay dilution. The dose of this medicine will be different for different patients. They may be taken with or without food, and at any time of day. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Explore careers. This content does not have an Arabic version.

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You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Toujeo is a prescription drug used to help manage blood sugar in type 1 and type 2 diabetes. Related Coverage. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Contact Us. Always follow the dosage that your doctor prescribes for you. Financial Assistance Documents — Florida. Admissions Requirements. Research Faculty. Research Faculty. Toujeo dosage Toujeo is a prescription drug used to help manage blood sugar in type 1 and type 2 diabetes.