Free radic biol med

Elsevier Inc. How to publish in this journal. The set of journals have been ranked according to their SJR and divided into four equal groups, four quartiles.

Free Radical Biology and Medicine is a peer-reviewed scientific journal and official journal of the Society for Redox Biology and Medicine. The journal covers research on redox biology, signaling, biological chemistry and medical implications of free radicals , reactive species, oxidants and antioxidants. This article about a biochemistry journal is a stub. You can help Wikipedia by expanding it. See tips for writing articles about academic journals.

Free radic biol med

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Impact factor. This indicator counts the number of citations received by documents from a journal and divides them by the total number of documents published in that journal.

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Extensive research during the past 2 decades has revealed the mechanism by which continued oxidative stress can lead to chronic inflammation, which in turn could mediate most chronic diseases including cancer, diabetes, and cardiovascular, neurological, and pulmonary diseases. Activation of these transcription factors can lead to the expression of over different genes, including those for growth factors, inflammatory cytokines, chemokines, cell cycle regulatory molecules, and anti-inflammatory molecules. How oxidative stress activates inflammatory pathways leading to transformation of a normal cell to tumor cell, tumor cell survival, proliferation, chemoresistance, radioresistance, invasion, angiogenesis, and stem cell survival is the focus of this review. Overall, observations to date suggest that oxidative stress, chronic inflammation, and cancer are closely linked. Abstract Extensive research during the past 2 decades has revealed the mechanism by which continued oxidative stress can lead to chronic inflammation, which in turn could mediate most chronic diseases including cancer, diabetes, and cardiovascular, neurological, and pulmonary diseases. Publication types Research Support, N.

Free radic biol med

Cardiovascular diseases CVD , including ischemic heart diseases and cerebrovascular diseases, are the leading causes of morbidity and mortality worldwide. Atherosclerosis is the major underlying factor for most CVD. It is well-established that oxidative stress and inflammation are two major mechanisms leading to atherosclerosis. Under oxidative stress, polyunsaturated fatty acids PUFA -containing phospholipids and cholesterol esters in cellular membrane and lipoproteins can be readily oxidized through a free radical-induced lipid peroxidation LPO process to form a complex mixture of oxidation products. Overwhelming evidence demonstrates that these oxidized lipids are actively involved in the inflammatory responses in atherosclerosis by interacting with immune cells such as macrophages and endothelial cells. In addition to lipid lowering in the prevention and treatment of atherosclerotic CVD, targeting chronic inflammation has been entering the medical realm. Clinical trials are under way to lower the lipoprotein a Lp a and its associated oxidized phospholipids, which will provide clinical evidence that targeting inflammation caused by oxidized lipids is a viable approach for CVD. In this review, we aim to give an update on our understanding of the free radical oxidation of LPO, analytical technique to analyze the oxidation products, especially the oxidized phospholipids and cholesterol esters in low density lipoproteins LDL , and focusing on the experimental and clinical evidence on the role of lipid oxidation in the inflammatory responses associated with CVD, including myocardial infarction and calcific aortic valve stenosis. Abstract Cardiovascular diseases CVD , including ischemic heart diseases and cerebrovascular diseases, are the leading causes of morbidity and mortality worldwide.

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All types of documents are considered, including citable and non citable documents. The purpose is to have a forum in which general doubts about the processes of publication in the journal, experiences and other issues derived from the publication of papers are resolved. Year SJR 1. This indicator counts the number of citations received by documents from a journal and divides them by the total number of documents published in that journal. Scope Free Radical Biology and Medicine is the premier forum for publishing groundbreaking research in the redox biology of both health and disease. Join the conversation about this journal. Elsevier Netherlands. Journal homepage Online access. The journal covers research on redox biology, signaling, biological chemistry and medical implications of free radicals , reactive species, oxidants and antioxidants. Further suggestions might be found on the article's talk page. Contents move to sidebar hide.

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The purpose is to have a forum in which general doubts about the processes of publication in the journal, experiences and other issues derived from the publication of papers are resolved. Journal homepage Online access. Year SJR 1. Year International Collaboration Kelvin Davies. How to publish in this journal. Join the conversation about this journal. Toggle limited content width. Year Documents SCImago Graphica Explore, visually communicate and make sense of data with our new data visualization tool.