Loci neo

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The extent of genetic degeneration of the neo-Y chromosome of Drosophila americana americana has been investigated. Three loci, coding for the enzymes enolase, phosphoglycerate kinase and alcohol dehydrogenase, have been localized to chromosome 4 of D. Crosses between D. Intercrosses between a genetically marked stock of virilis and strains of americana were carried out, creating F3 males that were homozygous for sections of the neo-Y chromosome. The sex ratios in the F3 generation of the intercrosses showed that no lethal alleles have accumulated on any of the neo-Y chromosomes tested. There was evidence for more minor reductions in fitness, but this seems to be mainly caused by deleterious alleles that are specific to each strain. A similar picture was provided by examination of the segregation ratios of two marker genes among the F3 progeny.

Loci neo

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This may not be the complete list of references from this article. The evolution of chromosomal sex determination and dosage compensation. Loci neo compensation of a retina-specific gene in Drosophila miranda.

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Thank you for visiting nature. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser or turn off compatibility mode in Internet Explorer. In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. Personality is influenced by genetic and environmental factors 1 and associated with mental health. However, the underlying genetic determinants are largely unknown. Of these genome-wide significant loci, extraversion was associated with variants in WSCD2 and near PCDH15 , and neuroticism with variants on chromosome 8p The first genetic dimension separated personality traits and psychiatric disorders, except that neuroticism and openness to experience were clustered with the disorders. High genetic correlations were found between extraversion and attention-deficit—hyperactivity disorder ADHD and between openness and schizophrenia and bipolar disorder. The second genetic dimension was closely aligned with extraversion—introversion and grouped neuroticism with internalizing psychopathology e.

Loci neo

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Dosage compensation regulatory proteins and the evolution of sex chromosomes in Drosophila. Biochem Genet. Articles from Genetics are provided here courtesy of Oxford University Press. Yu , and D. PMC Copyright notice. Three loci, coding for the enzymes enolase, phosphoglycerate kinase and alcohol dehydrogenase, have been localized to chromosome 4 of D. Do males of Drosophila littoralis have free recombination? Mol Biol Evol. Molecular phylogeny and genome evolution in the Drosophila virilis species group: duplications of the alcohol dehydrogenase gene. The effect of deleterious mutations on neutral molecular variation. As a library, NLM provides access to scientific literature. DNA sequence variation at the period locus reveals the history of species and speciation events in the Drosophila virilis group. Curr Biol.

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Annu Rev Genet. The origin and function of the mammalian Y chromosome and Y-borne genes--an evolving understanding. Dosage compensation and dietary glucose repression of larval amylase activity in Drosophila miranda. Molecular phylogeny and divergence times of drosophilid species. Charlesworth , D. The genetics of postzygotic isolation in the Drosophila virilis group. A similar picture was provided by examination of the segregation ratios of two marker genes among the F3 progeny. Hnilicka , A. The evolution of sex chromosomes. This may not be the complete list of references from this article.