Wellbutrin and jaw clenching

Why do SSRIs cause jaw clenching? While the exact mechanism is unknown, it appears that SSRIs trigger jaw clenching because of their effect on the level of neurotransmitters like serotonin in the brain. These neurotransmitters control mood, but they also contribute to movement regulation, wellbutrin and jaw clenching. Recent clinical evidence points to a significant association between selective serotonin reuptake inhibitor SSRI antidepressant drugs and jaw clenching.

We are incredibly fortunate to live in a time when some of our most painful and debilitating medical conditions can be well-controlled with prescription medications, allowing us to enjoy a more pleasurable quality of life. Jaw pain is a common complication that many people experience as the result of taking certain prescription medications for the treatment of other health conditions. Technically known as TMJ disorder, clenching and gritting the teeth can sometimes be triggered by the medications that are used to treat:. A number of medications that are used to treat these conditions can also trigger jaw problems, including:. These medications have been shown to lead to the unconscious habit of clenching or grinding the teeth, especially at night.

Wellbutrin and jaw clenching

Objective: To report a case of acute dystonia consisting of neck stiffness, trismus, and unilateral temporomandibular joint TMJ pain and subluxation secondary to an increase in sustained-release SR bupropion. Case summary: A year-old white man with a history of chronic low-back pain and tension headaches, taking no other medications, was started on bupropion SR mg once a day for depression. The dosage was increased to mg SR twice a day and eventually augmented with buspirone 15 mg 3 times a day. He developed bilateral trismus, inability to rotate his head laterally, and spontaneous left TMJ subluxation. Symptoms recessed with discontinuation of both medications and failed to reappear with a trial of buspirone 15 mg 3 times a day alone. A retrial of bupropion alone evidenced no adverse effects at a dosage of mg SR once a day. However, when the dosage was increased to mg SR twice a day, the patient reexperienced initial signs of neck stiffness, jaw muscle tightness, and left TMJ subluxation within hours. Discussion: Medication-induced focal dystonias usually present with dramatic head most frequently oral-buccal and neck muscle spasm with occasional jaw clenching, bruxism, and TMJ syndrome. In this case, the rapid onset of neck and jaw symptoms within hours of an increase of bupropion SR from mg once a day to mg twice a day suggest that the patient may have been sensitized by an initial trial of bupropion and buspirone, or by the increased dose of bupropion alone. Both agents are reported to interact with both the dopaminergic and serotonergic systems. Although buspirone has been implicated in inducing acute dystonia, it did not do so in this case when used alone at a dose of 45 mg a day. During a second trial of bupropion SR mg a day, neck and jaw symptoms recurred within hours of increasing the dose to mg SR twice a day. The symptoms receded when the bupropion dose was returned to mg SR once a day, suggesting a dose-response relationship.

According to the literature, stopping the SSRI should result in decreased jaw clenching within weeks.

Federal government websites often end in. The site is secure. Antidepressant-associated movement disorders are a well-described phenomenon. However, antidepressant-associated bruxism, jaw pain, or jaw spasm, while reported in dental literature, is less commonly recognized among neurologists. We summarize the clinical features and treatment of antidepressant-associated bruxism and associated jaw pain through a systematic review of case reports.

Objective: To report a case of acute dystonia consisting of neck stiffness, trismus, and unilateral temporomandibular joint TMJ pain and subluxation secondary to an increase in sustained-release SR bupropion. Case summary: A year-old white man with a history of chronic low-back pain and tension headaches, taking no other medications, was started on bupropion SR mg once a day for depression. The dosage was increased to mg SR twice a day and eventually augmented with buspirone 15 mg 3 times a day. He developed bilateral trismus, inability to rotate his head laterally, and spontaneous left TMJ subluxation. Symptoms recessed with discontinuation of both medications and failed to reappear with a trial of buspirone 15 mg 3 times a day alone. A retrial of bupropion alone evidenced no adverse effects at a dosage of mg SR once a day. However, when the dosage was increased to mg SR twice a day, the patient reexperienced initial signs of neck stiffness, jaw muscle tightness, and left TMJ subluxation within hours. Discussion: Medication-induced focal dystonias usually present with dramatic head most frequently oral-buccal and neck muscle spasm with occasional jaw clenching, bruxism, and TMJ syndrome.

Wellbutrin and jaw clenching

Our pharmacist answers the latest question regarding what to do if your SSRI causes jaw clenching. I'm on citalopram 40mgs daily, bupropion sr mgs daily, hydroxyzine 25mgs 3x daily, trazodone mgs nightly. Can any of one of these medications be a side affect causing my jaw to lock up. If so which one. My dentist said I only open 20 centimeters and it is not a dental issue. While not common, jaw clenching, grinding of teeth and a general condition known as bruxism CAN be caused by some of the medications you are taking including citalopram, trazodone and Wellbutrin. It is most commonly associated with the SSRI selective serotonin reuptake inhibitor you are taking, Celexa.

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Other studies are now revealing genetic variants in serotonin and dopamine receptors are associated with sleep bruxism. She was treated with a trial of onabotulinum toxin injections to the right masseter. Course Contents. While much depends on the type of injury or temporomandibular joint TMJ condition you have, using both is often optimal. J Child Adolesc Psychopharmacol ; 26 — Consequently, she had only been eating soft foods and chewing food on the left side of her mouth. More Articles. Int J Neuropsychopharmacol ; 7 — Int J Neuropsychopharmacol ; 9 — The case of spontaneous symptom resolution without intervention, as mentioned, reported resolution after 4 weeks. J Indian Prosthodont Soc ; 10 — Reports of SSRI-associated bruxism in the family physician's office. During a second trial of bupropion SR mg a day, neck and jaw symptoms recurred within hours of increasing the dose to mg SR twice a day. However, antidepressant-associated bruxism, jaw pain, or jaw spasm, while reported in dental literature, is less commonly recognized among neurologists. Although buspirone has been implicated in inducing acute dystonia, it did not do so in this case when used alone at a dose of 45 mg a day.

Temporomandibular joint disorder TMD is a broad pain disorder that refers to several conditions affecting the temporomandibular joint of the jaw and the muscles of mastication. As with most pain disorders, a high prevalence of depression and anxiety is associated with TMD. Research has shown that selective serotonin reuptake inhibitors SSRIs , the first-line drug therapy for major depressive disorder, may not be suitable for TMD patients because SSRIs can induce teeth-grinding, otherwise known as bruxism.

There are many different types of temporomandibular TMJ disorders, so the best mouth guard for TMJ pain depends on your underlying condition. Low-dose aripiprazole in the treatment of SSRI-induced bruxism. Please note that any medication changes should be directed by a healthcare professional. Call Us. Objective: To report a case of acute dystonia consisting of neck stiffness, trismus, and unilateral temporomandibular joint TMJ pain and subluxation secondary to an increase in sustained-release SR bupropion. However, she was concerned that her jaw pain may have been related to her SSRI, revealing that her symptoms started soon after she began this medicine 2 years prior. J Clin Psychopharmacol ; 34 During a second trial of bupropion SR mg a day, neck and jaw symptoms recurred within hours of increasing the dose to mg SR twice a day. This phenomenon may be seen in a variety of serotonergic antidepressants, and may be most associated with fluoxetine, sertraline, or venlafaxine. We are incredibly fortunate to live in a time when some of our most painful and debilitating medical conditions can be well-controlled with prescription medications, allowing us to enjoy a more pleasurable quality of life. While much depends on the type of injury or temporomandibular joint TMJ condition you have, using both is often optimal.